Description
Pregabalin powder video
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Pregabalin powder reviews
Pregabalin powder is a white powder used as an antiepileptic drug, also called an anticonvulsant. It works by slowing down the impulses in the brain that cause seizures. Pregabalin powder also affects chemicals in the brain that send pain signals through the nervous system.
Pregabalin powder is used to treat pain caused by fibromyalgia or nerve pain in people with diabetes (diabetic neuropathy), herpes zoster (post-herpetic neuralgia), or spinal cord injury.
Pregabalin powder is also used with other medications to treat partial-onset seizures in adults and children at least 1 month of age. Pregabalin raw powder can also be used for purposes not listed in this medication guide.
Pregabalin mechanism of action
Pregabalin is an anticonvulsant drug used to treat neuropathic pain and fibromyalgia conditions and to treat partial-onset seizures in combination with other anticonvulsants.
Although the mechanism of action has not been fully elucidated, studies involving structurally related drugs suggest that the presynaptic binding of pregabalin to voltage-gated calcium channels is key to the antiepileptic and antinociceptive effects observed in animal models.
By presynaptically binding to the alpha2-delta subunit of voltage-gated calcium channels in the central nervous system, pregabalin modulates the release of numerous excitatory neurotransmitters including glutamate, P-substance, noradrenaline, and calcitonin gene-related peptide. Furthermore, pregabalin prevents the alpha2-delta subunit from trafficking from the dorsal root ganglia to the spinal dorsal horn, which may also contribute to the mechanism of action. Although pregabalin is a structural derivative of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA), it does not bind directly to GABA or benzodiazepine receptors.
Uses / Application by Pregabalin
❶ Pharmacological efficacy: Pregabalin is a γ-aminobutyric acid (GABA) receptor agonist, it can block voltage-gated calcium channels to reduce the release of neurotransmitters.
❷ Leading clinic for the treatment of peripheral neuropathic pain as well as part of the adjuvant treatment of focal seizures.
❸ Treatment of epilepsy in the development of the most promising drug in a better and more convenient administration drug treatment. It can also be used to treat pain and anxiety.
Pregabalin side effects
Like most medications, Lyrica can cause mild or severe side effects. This is not a complete list of side effects and others may occur. A health care practitioner can advise you on side effects. If other effects occur, contact your pharmacist or healthcare professional.
Common side effects
Side effects may occur when taking pregabalin. Common side effects of pregabalin include:
▪ dizziness
▪ sleepiness
▪ confusion
▪ blurred vision
▪ tremor
▪ instability when walking
▪ weight gain
Constipation
▪ dry mouth.
Serious side effects
Call your provider right away if you have severe side effects. Call 911 if your symptoms seem life-threatening or if you think you have a medical emergency. Serious side effects and their symptoms can include the following:
▪ Suicidal thoughts or suicide attempts: Symptoms may include suicide attempts, new or worsening anxiety or depression, sleep disturbances, agitation, acting on dangerous urges and unusual changes in mood or behavior.
▪ Severe allergic reactions: Symptoms may include difficulty breathing, hives and swelling of the tongue, lips, mouth or throat.
▪ Heart problems
▪ Severe breathing problems
Some side effects may improve over time, while others such as dizziness and sleepiness may last as long as you take the medicine.
Pregabalin storage
People should store this drug at a controlled room temperature, around 68 degrees to 77 degrees Fahrenheit.
If you travel, always carry your medications with you and keep the original bottle or box with the prescription label in your hand luggage. Do not leave this drug in the car, especially in very cold or hot temperatures.
AASraw Pregabalin Powder Buying Guide Step by Step
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Reference
[1] Dworkin RH, O'Connor AB, Backonja M, et al. Pharmacological management of neuropathic pain: evidence-based recommendations. Pain 2007,132: 237-51. [2] Finnerup NB, Jensen TS. Clinical use of pregabalin in the management of central neuropathic pain. Neuropsychiatric Diseases and Care 2007,3: 885-91. [3] Kalso E, Aldington DJ, Moore RA. Neuropathic pain medications. BMJ 2013,347: f7339. [4] Mannix, Liam (December 18, 2018). “This popular drug is linked to addiction and suicide. Why do doctors keep prescribing it? ”. The Canberra Times. Archived from the original on 18 December 2018. Retrieved December 18, 2018. [5] However, James W., Willmore, James, Brumback, Roger A. (2009). Advanced therapy in epilepsy. PMPH-USA. p. 302. ISBN 978-1-60795-004-2.
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