Urolithin A

Description

Basic features

product name Urolithin A CAS number 1143-70-0 Molecular formula C13H8O4 Weight Formula 228.2 Synonyms 2 ', 7-Dihydroxy-3,4-benzocoumarin

3,8-dihydroxy urolithin,

Urolithin A 8-methyl ether,

3-hydroxy-8-methoxy-6H-dibenzo [b, d] pyran-6-one.

Form White crystalline powder Storage and management Dry, dark and 0 – 4 C for a short time (days to weeks) or -20 C for a long time (months to years).

Reference

[1] Spendiff, S. et al. Mitochondrial DNA deletions in muscle satellite cells: implications for therapies. Hum. Mol. Genet. 22, 4739–4747 (2013) [2] Bialonska D, Kasimsetty SG, Khan SI, Ferreira D (11 November 2009). 'Urolithins, intestinal microbial metabolites of pomegranate ellagitannins, show potent antioxidant activity in a cell assay.' J Agric Food Chem. 57 (21): 10181-6. doi: 10.1021 / jf9025794. PMID 19824638. [3] Milburn, MV & Lawton, KA Application of metabolomics to the diagnosis of insulin resistance. Nodded. Rev. Med. 64, 291-305 (2013). [4] Cerdá, Begoña, Tomás-Barberán, Francisco A., Espín, Juan Carlos (2005). 'Metabolism of antioxidant and chemopreventive ellagitannins from strawberries, raspberries, walnuts and oak-aged wine in humans: identification of biomarkers and individual variability'. Journal of Agricultural and Food Chemistry. 53 (2): 227-235. doi: 10.1021 / jf049144d. PMID 15656654. [5] Laker, RC et al. Ampk phosphorylation of Ulk1 is required to target mitochondria to lysosomes in exercise-induced mitophagy. Nat.Commun. 8, 548 (2017).